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Nucleolar stress in Drosophila melanogaster: RNAi-mediated depletion of Nopp140
Nucleolar stress results when ribosome biogenesis is disrupted. An excellent example is the human Treacher Collins syndrome in which the loss of the nucleolar chaperone, Treacle, leads to p53-dependent apoptosis in embryonic neural crest cells and ultimately to craniofacial birth defects. Here, we s...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3621744/ https://ncbi.nlm.nih.gov/pubmed/23412656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.23944 |
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