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Nucleolar stress in Drosophila melanogaster: RNAi-mediated depletion of Nopp140

Nucleolar stress results when ribosome biogenesis is disrupted. An excellent example is the human Treacher Collins syndrome in which the loss of the nucleolar chaperone, Treacle, leads to p53-dependent apoptosis in embryonic neural crest cells and ultimately to craniofacial birth defects. Here, we s...

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Detalhes bibliográficos
Main Authors: James, Allison, Cindass Jr, Renford, Mayer, Dana, Terhoeve, Stephanie, Mumphrey, Courtney, DiMario, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621744/
https://ncbi.nlm.nih.gov/pubmed/23412656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.23944
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