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Evaluation of A Novel Arg-Gly-Asp-Conjugated Alpha-Melanocyte Stimulating Hormone Hybrid Peptide for Potential Melanoma Therapy

The purpose of this study was to determine whether Arg-Gly-Asp (RGD)-conjugated alpha-melanocyte stimulating hormone (α-MSH) hybrid peptide could be employed to target melanocortin-1 (MC1) receptor for potential melanoma therapy. METHODS: The RGD motif {cyclic(Arg-Gly-Asp-DTyr-Asp)} was coupled to [...

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Detalhes bibliográficos
Main Authors: Yang, Jianquan, Guo, Haixun, Gallazzi, Fabio, Berwick, Marianne, Padilla, R. Steven, Miao, Yubin
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621710/
https://ncbi.nlm.nih.gov/pubmed/19552406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc9001954
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