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Role of arachidonic acid metabolism in transcriptional induction of tumor necrosis factor gene expression by phorbol ester.

The treatment of human HL-60 promyelocytic leukemia cells with 12-O-tetradecanoylphorbol-13-acetate (TPA) is associated with induction of tumor necrosis factor (TNF) transcript. The study reported here has examined TPA-induced signaling mechanisms responsible for the regulation of TNF gene expressio...

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Detalhes bibliográficos
Main Authors: Horiguchi, J, Spriggs, D, Imamura, K, Stone, R, Luebbers, R, Kufe, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC362167/
https://ncbi.nlm.nih.gov/pubmed/2494431
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