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Role of arachidonic acid metabolism in transcriptional induction of tumor necrosis factor gene expression by phorbol ester.

The treatment of human HL-60 promyelocytic leukemia cells with 12-O-tetradecanoylphorbol-13-acetate (TPA) is associated with induction of tumor necrosis factor (TNF) transcript. The study reported here has examined TPA-induced signaling mechanisms responsible for the regulation of TNF gene expressio...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Horiguchi, J, Spriggs, D, Imamura, K, Stone, R, Luebbers, R, Kufe, D
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1989
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362167/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2494431/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.1.252-258.1989
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