Effects of early life exposure to ultraviolet C radiation on mitochondrial DNA content, transcription, ATP production, and oxygen consumption in developing Caenorhabditis elegans

BACKGROUND: Mitochondrial DNA (mtDNA) is present in multiple copies per cell and undergoes dramatic amplification during development. The impacts of mtDNA damage incurred early in development are not well understood, especially in the case of types of mtDNA damage that are irreparable, such as ultra...

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Autors principals: Leung, Maxwell CK, Rooney, John P, Ryde, Ian T, Bernal, Autumn J, Bess, Amanda S, Crocker, Tracey L, Ji, Alex Q, Meyer, Joel N
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621653/
https://ncbi.nlm.nih.gov/pubmed/23374645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-14-9
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