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Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome

Induced pluripotent stem cells (iPSC) have been generated from somatic cells by introducing reprogramming factors. Integration of foreign genes into the host genome is a technical hurdle for the clinical application. Here, we show that Sendai virus (SeV), an RNA virus and carries no risk of altering...

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Bibliografische gegevens
Hoofdauteurs: Fusaki, Noemi, Ban, Hiroshi, Nishiyama, Akiyo, Saeki, Koichi, Hasegawa, Mamoru
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Japan Academy 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621571/
https://ncbi.nlm.nih.gov/pubmed/19838014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab.85.348
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