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Construction and properties of replication-competent murine retroviral vectors encoding methotrexate resistance.

A series of replication-competent Moloney murine leukemia virus vectors was constructed in which each vector contained a mutant dihydrofolate reductase (DHFR) cDNA insert in the U3 region of the viral long terminal repeat. Two of the resulting viruses, MLV (murine leukemia virus) DHFR*-5 and MLV DHF...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Stuhlmann, H, Jaenisch, R, Mulligan, R C
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1989
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362150/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2927389/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.1.100-108.1989
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