VEGF internalization is not required for VEGFR-2 phosphorylation in bioengineered surfaces with covalently linked VEGF

Vascular endothelial growth factor (VEGF) is known to activate proliferation, migration, and survival pathways in endothelial cells through phosphorylation of VEGF receptor-2 (VEGFR-2). VEGF has been incorporated into biomaterials through encapsulation, electrostatic sequestration, and covalent atta...

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Библиографические подробности
Главные авторы: Anderson, Sean M., Shergill, Bhupinder, Barry, Zachary T., Manousiouthakis, Eleana, Chen, Tom T., Botvinick, Elliot, Platt, Manu O., Iruela-Arispe, M. Luisa, Segura, Tatiana
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621282/
https://ncbi.nlm.nih.gov/pubmed/21826315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1ib00037c
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