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Autosomal dominant polycystic kidney disease in a family with mosaicism and hypomorphic allele

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is the most common form of inherited kidney disease that results in renal failure. ADPKD is a systemic disorder with cysts and connective tissue abnormalities involving many organs. ADPKD caused by mutations in PKD1 gene is significant...

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Bibliografski detalji
Glavni autori: Reiterová, Jana, Štekrová, Jitka, Merta, Miroslav, Kotlas, Jaroslav, Elišáková, Veronika, Lněnička, Petr, Korabečná, Marie, Kohoutová, Milada, Tesař, Vladimír
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621255/
https://ncbi.nlm.nih.gov/pubmed/23496908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-14-59
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