Experimental arthritis in CC chemokine receptor 2–null mice closely mimics severe human rheumatoid arthritis

The prevailing paradigm is that in human rheumatoid arthritis (RA), the accumulation of monocytes and T cells in the joint, mediated in part by such CC chemokine receptors (CCRs) as CCR2 and CCR5, respectively, plays a central role in disease pathogenesis. To further validate this paradigm, we condu...

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Detalhes bibliográficos
Main Authors: Quinones, Marlon P., Ahuja, Sunil K., Jimenez, Fabio, Schaefer, Jason, Garavito, Edgar, Rao, Arun, Chenaux, George, Reddick, Robert L., Kuziel, William A., Ahuja, Seema S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC362121/
https://ncbi.nlm.nih.gov/pubmed/15067318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420126
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