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Effective treatment with a tetrandrine/chloroquine combination for chloroquine-resistant falciparum malaria in Aotus monkeys

BACKGROUND: In vitro evidence indicates that tetrandrine (TT) can potentiate the action of chloroquine 40-fold against choloquine-resistant Plasmodium falciparum. The key question emanating from that study is “would tetrandine and chloroquine be highly effective in a live Aotus monkey model with chl...

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Detalhes bibliográficos
Main Authors: Ye, Zuguang, Van Dyke, Knox, Rossan, Richard N
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621158/
https://ncbi.nlm.nih.gov/pubmed/23547773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-117
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