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DNA vaccination with CD25 protects rats from adjuvant arthritis and induces an antiergotypic response
Ab’s to the α-chain of the IL-2 receptor (anti-CD25) are used clinically to achieve immunosuppression. Here we investigated the effects of DNA vaccination with the whole CD25 gene on the induction of rat adjuvant arthritis. The DNA vaccine protected the rats and led to a shift in the cytokine profil...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC362112/ https://ncbi.nlm.nih.gov/pubmed/15067325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200417772 |
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