The Tiotropium Safety and Performance in Respimat® Trial (TIOSPIR®), a large scale, randomized, controlled, parallel-group trial-design and rationale

BACKGROUND: Tiotropium bromide is an effective therapy for COPD patients. Comparing across programs tiotropium Respimat® Soft Mist™ inhaler was at least as efficacious as tiotropium HandiHaler®, however, concerns have been raised about tiotropium’s safety when given via Respimat®. METHODS: The TIOSP...

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Main Authors: Wise, Robert A, Anzueto, Antonio, Calverley, Peter, Dahl, Ronald, Dusser, Daniel, Pledger, Gordon, Koenen-Bergmann, Michael, Joseph, Elizabeth, Cotton, Daniel, Disse, Bernd
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621103/
https://ncbi.nlm.nih.gov/pubmed/23547660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-14-40
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