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Impaired prefrontostriatonigral functional connectivity and substantia nigra hyperactivity in schizophrenia

BACKGROUND: The theory that prefrontal cortex (PFC) dysfunction in schizophrenia leads to excess subcortical dopamine (DA) has generated widespread interest because it provides a parsimonious account for two core features of schizophrenia, cognitive deficits and psychosis, respectively. However, the...

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Autors principals: Yoon, Jong H., Minzenberg, Michael J., Raouf, Sherief, D'Esposito, Mark, Carter, Cameron S.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620727/
https://ncbi.nlm.nih.gov/pubmed/23290498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2012.11.018
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