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Increased carbonylation, protein aggregation and apoptosis in the spinal cord of mice with experimental autoimmune encephalomyelitis

Previous work from our laboratory implicated protein carbonylation in the pathophysiology of both MS (multiple sclerosis) and its animal model EAE (experimental autoimmune encephalomyelitis). Subsequent in vitro studies revealed that the accumulation of protein carbonyls, triggered by glutathione de...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dasgupta, Anushka, Zheng, Jianzheng, Perrone-Bizzozero, Nora I., Bizzozero, Oscar A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Neurochemistry 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620690/
https://ncbi.nlm.nih.gov/pubmed/23489322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20120088
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