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Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells

BACKGROUND: For safe clinical application of engineered cartilage made from mesenchymal stem cells (MSCs), molecular mechanisms for chondrogenic differentiation must be known in detail. Changes in gene expression and extracellular matrix synthesis have been extensively studied, but the epigenomic mo...

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Detaylı Bibliyografya
Asıl Yazarlar: Herlofsen, Sarah R, Bryne, Jan Christian, Høiby, Torill, Wang, Li, Issner, Robbyn, Zhang, Xiaolan, Coyne, Michael J, Boyle, Patrick, Gu, Hongcang, Meza-Zepeda, Leonardo A, Collas, Philippe, Mikkelsen, Tarjei S, Brinchmann, Jan E
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620534/
https://ncbi.nlm.nih.gov/pubmed/23414147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-105
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