Willin, an Upstream Component of the Hippo Signaling Pathway, Orchestrates Mammalian Peripheral Nerve Fibroblasts

Willin/FRMD6 was first identified in the rat sciatic nerve, which is composed of neurons, Schwann cells, and fibroblasts. Willin is an upstream component of the Hippo signaling pathway, which results in the inactivation of the transcriptional co-activator YAP through Ser127 phosphorylation. This in...

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Bibliografische gegevens
Hoofdauteurs: Moleirinho, Susana, Patrick, Calum, Tilston-Lünel, Andrew M., Higginson, Jennifer R., Angus, Liselotte, Antkowiak, Maciej, Barnett, Susan C., Prystowsky, Michael B., Reynolds, Paul A., Gunn-Moore, Frank J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620498/
https://ncbi.nlm.nih.gov/pubmed/23593160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060028
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