Assessing the Effects of Aedes aegypti kdr Mutations on Pyrethroid Resistance and Its Fitness Cost

Pyrethroids are the most used insecticide class worldwide. They target the voltage gated sodium channel (Na(V)), inducing the knockdown effect. In Aedes aegypti, the main dengue vector, the AaNa(V) substitutions Val1016Ile and Phe1534Cys are the most important knockdown resistance (kdr) mutations. W...

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Main Authors: Brito, Luiz Paulo, Linss, Jutta G. B., Lima-Camara, Tamara N., Belinato, Thiago A., Peixoto, Alexandre A., Lima, José Bento P., Valle, Denise, Martins, Ademir J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620451/
https://ncbi.nlm.nih.gov/pubmed/23593337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060878
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