Transgenic Overexpression of Interleukin-1β Induces Persistent Lymphangiogenesis But Not Angiogenesis in Mouse Airways

These studies used bi-transgenic Clara cell secretory protein (CCSP)/IL-1β mice that conditionally overexpress IL-1β in Clara cells to determine whether IL-1β can promote angiogenesis and lymphangiogenesis in airways. Doxycycline treatment induced rapid, abundant, and reversible IL-1β production, in...

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Detalles Bibliográficos
Autores principales: Baluk, Peter, Hogmalm, Anna, Bry, Maija, Alitalo, Kari, Bry, Kristina, McDonald, Donald M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2013
Materias:
Regular Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620402/
https://ncbi.nlm.nih.gov/pubmed/23391392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.12.003
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