Fatty Acid Binding Protein 4 Regulates VEGF-Induced Airway Angiogenesis and Inflammation in a Transgenic Mouse Model: Implications for Asthma

Neovascularization of the airways occurs in several inflammatory lung diseases, including asthma. Vascular endothelial growth factor (VEGF) plays an important role in vascular remodeling in the asthmatic airways. Fatty acid binding protein 4 (FABP4 or aP2) is an intracellular lipid chaperone that is...

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Autores principales: Ghelfi, Elisa, Yu, Chen-Wei, Elmasri, Harun, Terwelp, Matthew, Lee, Chun G., Bhandari, Vineet, Comhair, Suzy A., Erzurum, Serpil C., Hotamisligil, Gökhan S., Elias, Jack A., Cataltepe, Sule
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2013
Materias:
Regular Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620401/
https://ncbi.nlm.nih.gov/pubmed/23391391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.12.009
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