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Radiation-Induced Lung Injury Is Mitigated by Blockade of Gastrin-Releasing Peptide

Gastrin-releasing peptide (GRP), secreted by pulmonary neuroendocrine cells, mediates oxidant-induced lung injury in animal models. Considering that GRP blockade abrogates pulmonary inflammation and fibrosis in hyperoxic baboons, we hypothesized that ionizing radiation triggers GRP secretion, contri...

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Bibliografische gegevens
Hoofdauteurs: Zhou, Shutang, Nissao, Esther, Jackson, Isabel L., Leong, Wei, Dancy, Lindsay, Cuttitta, Frank, Vujaskovic, Zeljko, Sunday, Mary E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Investigative Pathology 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620399/
https://ncbi.nlm.nih.gov/pubmed/23395092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.12.024
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