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Radiation-Induced Lung Injury Is Mitigated by Blockade of Gastrin-Releasing Peptide
Gastrin-releasing peptide (GRP), secreted by pulmonary neuroendocrine cells, mediates oxidant-induced lung injury in animal models. Considering that GRP blockade abrogates pulmonary inflammation and fibrosis in hyperoxic baboons, we hypothesized that ionizing radiation triggers GRP secretion, contri...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3620399/ https://ncbi.nlm.nih.gov/pubmed/23395092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.12.024 |
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