Genetically Determined Severity of Anti-Myeloperoxidase Glomerulonephritis

Myeloperoxidase (MPO) is a target antigen for antineutrophil cytoplasmic autoantibodies (ANCA). There is evidence that MPO-ANCA cause necrotizing and crescentic glomerulonephritis (NCGN) and vasculitis. NCGN severity varies among patients with ANCA disease, and genetic factors influence disease seve...

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Bibliografiske detaljer
Main Authors: Xiao, Hong, Ciavatta, Dominic, Aylor, David L., Hu, Peiqi, de Villena, Fernando Pardo-Manuel, Falk, Ronald J., Jennette, J. Charles
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2013
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620395/
https://ncbi.nlm.nih.gov/pubmed/23384999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.12.006
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