Lung-resident tissue macrophages generate Foxp3(+) regulatory T cells and promote airway tolerance

Airway tolerance is the usual outcome of inhalation of harmless antigens. Although T cell deletion and anergy are likely components of tolerogenic mechanisms in the lung, increasing evidence indicates that antigen-specific regulatory T cells (inducible T(reg) cells [iT(reg) cells]) that express Foxp...

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Hauptverfasser: Soroosh, Pejman, Doherty, Taylor A., Duan, Wei, Mehta, Amit Kumar, Choi, Heonsik, Adams, Yan Fei, Mikulski, Zbigniew, Khorram, Naseem, Rosenthal, Peter, Broide, David H., Croft, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620360/
https://ncbi.nlm.nih.gov/pubmed/23547101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121849
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