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PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis
Immune responses to persistent viral infections and cancer often fail because of intense regulation of antigen-specific T cells—a process referred to as immune exhaustion. The mechanisms that underlie the induction of exhaustion are not completely understood. To gain novel insights into this process...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3620347/ https://ncbi.nlm.nih.gov/pubmed/23530125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121416 |
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