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The Process and Development Mechanism of Age-related Fibrosis in the Pancreatic Islets of Sprague-Dawley Rats: Immunohistochemical Detection of Myofibroblasts and Suppression Effect by Estrogen Treatment

The mechanism of spontaneous islet fibrosis in Sprague-Dawley rats was investigated. Using sections of the pancreas in naive males aged 26 to 102 weeks old and 26-week-old males injected with β-estradiol 3-benzoate (EB), the incidence of lesions and histological scores of fibrosis were examined in c...

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Detalhes bibliográficos
Main Authors: Imaoka, Masako, Jindo, Toshimasa, Takasaki, Wataru
Formato: Artigo
Idioma:Inglês
Publicado em: Japanese Society of Toxicologic Pathology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620208/
https://ncbi.nlm.nih.gov/pubmed/23723562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.26.1
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