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Effects of phosphatase and proteasome inhibitors on Borealin phosphorylation and degradation

The chromosomal passenger complex (CPC) senses tension defects at the kinetochore to activate the spindle assembly checkpoint, and helps to position the cleavage furrow. The CPC, consisting of INCENP, Survivin, Borealin and Aurora B localizes to the inner centromere at metaphase and re-localizes to...

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Autori principali: Date, Dipali, Dreier, Megan R., Borton, Michael T., Bekier, Michael E., Taylor, William R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619963/
https://ncbi.nlm.nih.gov/pubmed/22383538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jb/mvs015
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