Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: Systematic review and meta-analysis of 14 015 stroke cases and pooled analysis of primary biomarker data from up to 60 883 individuals

Background At the APOE gene, encoding apolipoprotein E, genotypes of the ε2/ε3/ε4 alleles associated with higher LDL-cholesterol (LDL-C) levels are also associated with higher coronary risk. However, the association of APOE genotype with other cardiovascular biomarkers and risk of ischaemic stroke i...

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Bibliografiska uppgifter
Huvudupphovsmän: Khan, Tauseef A, Shah, Tina, Prieto, David, Zhang, Weili, Price, Jackie, Fowkes, Gerald R, Cooper, Jackie, Talmud, Philippa J, Humphries, Steve E, Sundstrom, Johan, Hubacek, Jaroslav A, Ebrahim, Shah, Lawlor, Debbie A, Ben-Shlomo, Yoav, Abdollahi, Mohammad R, Slooter, Arjen JC, Szolnoki, Zoltan, Sandhu, Manjinder, Wareham, Nicholas, Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Fillenbaum, Gerda, Heijmans, Bastiaan T, Katsuya, Tomohiro, Gromadzka, Grazyna, Singleton, Andrew, Ferrucci, Luigi, Hardy, John, Worrall, Bradford, Rich, Stephen S, Matarin, Mar, Whittaker, John, Gaunt, Tom R, Whincup, Peter, Morris, Richard, Deanfield, John, Donald, Ann, Davey Smith, George, Kivimaki, Mika, Kumari, Meena, Smeeth, Liam, Khaw, Kay-Tee, Nalls, Michael, Meschia, James, Sun, Kai, Hui, Rutai, Day, Ian, Hingorani, Aroon D, Casas, Juan P
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2013
Ämnen:
Genetic and Molecular Epidemiology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619955/
https://ncbi.nlm.nih.gov/pubmed/23569189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyt034
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