Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: Systematic review and meta-analysis of 14 015 stroke cases and pooled analysis of primary biomarker data from up to 60 883 individuals

Background At the APOE gene, encoding apolipoprotein E, genotypes of the ε2/ε3/ε4 alleles associated with higher LDL-cholesterol (LDL-C) levels are also associated with higher coronary risk. However, the association of APOE genotype with other cardiovascular biomarkers and risk of ischaemic stroke i...

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Main Authors: Khan, Tauseef A, Shah, Tina, Prieto, David, Zhang, Weili, Price, Jackie, Fowkes, Gerald R, Cooper, Jackie, Talmud, Philippa J, Humphries, Steve E, Sundstrom, Johan, Hubacek, Jaroslav A, Ebrahim, Shah, Lawlor, Debbie A, Ben-Shlomo, Yoav, Abdollahi, Mohammad R, Slooter, Arjen JC, Szolnoki, Zoltan, Sandhu, Manjinder, Wareham, Nicholas, Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Fillenbaum, Gerda, Heijmans, Bastiaan T, Katsuya, Tomohiro, Gromadzka, Grazyna, Singleton, Andrew, Ferrucci, Luigi, Hardy, John, Worrall, Bradford, Rich, Stephen S, Matarin, Mar, Whittaker, John, Gaunt, Tom R, Whincup, Peter, Morris, Richard, Deanfield, John, Donald, Ann, Davey Smith, George, Kivimaki, Mika, Kumari, Meena, Smeeth, Liam, Khaw, Kay-Tee, Nalls, Michael, Meschia, James, Sun, Kai, Hui, Rutai, Day, Ian, Hingorani, Aroon D, Casas, Juan P
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Genetic and Molecular Epidemiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619955/
https://ncbi.nlm.nih.gov/pubmed/23569189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyt034
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