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Toxicological and Toxicokinetic Analysis of Angiotensin (1–7) in Two Species

The objectives of this study were to determine the potential systemic and local toxicity, as well as evaluate the toxicokinetic (TK) profile of angiotensin (1–7) [A(1–7)] when administered daily via subcutaneous injection for 28 days to Sprague–Dawley rats and Beagle dogs. A(1–7) is a member of the...

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Detalhes bibliográficos
Main Authors: Mordwinkin, Nicholas M., Russell, Jared R., Burke, Angela S., Dizerega, Gere S., Louie, Stan. G., Rodgers, Kathleen E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619381/
https://ncbi.nlm.nih.gov/pubmed/21858825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.22730
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