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SCAR/WAVE-mediated processing of engulfed apoptotic corpses is essential for effective macrophage migration in Drosophila

In vitro studies have shown that SCAR/WAVE activates the Arp2/3 complex to generate actin filaments, which in many cell types are organised into lamellipodia that are thought to have an important role in cell migration. Here we demonstrate that SCAR is utilised by Drosophila macrophages to drive the...

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Bibliographic Details
Main Authors: Evans, I R, Ghai, P A, Urbančič, V, Tan, K-L, Wood, W
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619236/
https://ncbi.nlm.nih.gov/pubmed/23328632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.166
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