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Targeting liver cancer – first steps towards a miRacle?

In a recent issue of Cell, Iliopoulos and colleagues demonstrate a novel and targetable epigenetic amplification loop in hepatocellular carcinoma involving HNF4α, miR-124, IL6-R, Stat3, miR-24 and miR-629. These results establish microRNAs as novel players in early stages of hepatocarcinogenesis and...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Schwabe, Robert F., Wang, Timothy C.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619204/
https://ncbi.nlm.nih.gov/pubmed/22172719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.11.021
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