A randomised double-blind placebo-controlled phase II study of AGI004 for control of chemotherapy-induced diarrhoea

BACKGROUND: AGI004 is a controlled-release transdermal patch preparation of mecamylamine. We conducted a randomised placebo-controlled phase II study of two dose levels of AGI004 in chemotherapy-induced diarrhoea (CID). METHODS: Adult patients receiving chemotherapy who had experienced diarrhoea (NC...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Coyle, V M, Lungulescu, D, Toganel, C, Niculescu, A, Pop, S, Ciuleanu, T, Cebotaru, C, Devane, J, Martin, M, Wilson, R H
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2013
Sujets:
Clinical Study
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619064/
https://ncbi.nlm.nih.gov/pubmed/23462724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.35
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