Polymeric Nanoparticle-Based Activatable Near-Infrared Nanosensor for Protease Determination In Vivo

We report here a new protease activatable strategy based on a polymer nanoparticle platform. This nanosensor delivers chemically labeled matrix metalloproteinase (MMP)-activatable fluorogenic peptides to the specific MMPs of interest in vivo. Intravenous administration of the nanosensor in an MMP-po...

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Detalhes bibliográficos
Main Authors: Lee, Seulki, Ryu, Ju Hee, Park, Kyeongsoon, Lee, Aeju, Lee, Seung-Young, Youn, In-Chan, Ahn, Cheol-Hee, Yoon, Soon Man, Myung, Seung-Jae, Moon, Dae Hyuk, Chen, Xiaoyuan, Choi, Kuiwon, Kwon, Ick Chan, Kim, Kwangmeyung
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618996/
https://ncbi.nlm.nih.gov/pubmed/19842672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl902709m
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