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Quantitative screening of genes regulating tryptophan hydroxylase transcription in C. elegans using microfluidics and adaptive algorithm

Forward genetic screen via mutagenesis is a powerful method for identifying regulatory factors in target pathways in model organisms such as the soil-dwelling free-living nematode Caenorhabditis elegans (C. elegans). Currently manual microscopy is the standard technique for conducting such screens;...

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Detalhes bibliográficos
Main Authors: Lee, Hyewon, Crane, Matthew M., Zhang, Yun, Lu, Hang
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618955/
https://ncbi.nlm.nih.gov/pubmed/23168494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2ib20078c
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