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17-β Estradiol reduces atherosclerosis without exacerbating lupus in ovariectomized systemic lupus erythematosus-susceptible LDLr(−/−) mice

OBJECTIVE: To test the hypothesis that estrogen treatment in a radiation chimera mouse model of systemic lupus erythematosus (SLE) and atherosclerosis will increase SLE-associated atherosclerosis by increasing autoantibody production and inflammation. METHODS: We used a radiation chimera mouse model...

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Bibliografske podrobnosti
Main Authors: Shelton, KA, Cline, JM, Cann, JA
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618855/
https://ncbi.nlm.nih.gov/pubmed/23395521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2012.12.031
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