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ACA-specific RNA sequence recognition is acquired via the loop 2 region of MazF mRNA interferase
MazF is an mRNA interferase that cleaves mRNAs at a specific RNA sequence. MazF from E. coli (MazF-ec) cleaves RNA at A^CA. To date, a large number of MazF homologues that cleave RNA at specific three- to seven-base sequences have been identified from bacteria to archaea. MazF-ec forms a dimer, in w...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3618565/ https://ncbi.nlm.nih.gov/pubmed/23280569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24246 |
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