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ACA-specific RNA sequence recognition is acquired via the loop 2 region of MazF mRNA interferase

MazF is an mRNA interferase that cleaves mRNAs at a specific RNA sequence. MazF from E. coli (MazF-ec) cleaves RNA at A^CA. To date, a large number of MazF homologues that cleave RNA at specific three- to seven-base sequences have been identified from bacteria to archaea. MazF-ec forms a dimer, in w...

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Autores principales: Park, Jung-Ho, Yoshizumi, Satoshi, Yamaguchi, Yoshihiro, Wu, Kuen-Phon, Inouye, Masayori
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618565/
https://ncbi.nlm.nih.gov/pubmed/23280569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24246
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