Isoprenoid pathway activity is required for IgE receptor-mediated, tyrosine kinase-coupled transmembrane signaling in permeabilized RBL-2H3 rat basophilic leukemia cells.

Previously, we reported that the isoprenoid pathway inhibitor, lovastatin, blocks the activation by IgE receptor cross-linking of 45Ca2+ influx, 1,4,5-inositol trisphosphate production, secretion, and membrane changes (ruffling, spreading) in intact RBL-2H3 rat basophilic leukemia cells. These resul...

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Detalhes bibliográficos
Main Authors: Deanin, G G, Pfeiffer, J R, Cutts, J L, Fore, M L, Oliver, J M
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC361853/
https://ncbi.nlm.nih.gov/pubmed/1777505
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