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IL-22 reduces the severity of collagen arthritis in association with increased levels of IL-10

OBJECTIVE: The mechanism of action of IL-22 in inflammatory arthritis remains unknown. IL-22 deficient mice have intact humoral and cellular immune response to collagen and yet have a reduced incidence of collagen induced arthritis. Further, administration of anti-IL-22 does not reduce severity of c...

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Detalhes bibliográficos
Main Authors: Sarkar, Sujata, Zhou, Xiaoqun, Justa, Shivali, Bommireddy, Swaroopa Rani
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618496/
https://ncbi.nlm.nih.gov/pubmed/23334981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.37849
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