Hypoxia-inducible factor 1 is essential for spontaneous recovery from traumatic brain injury and is a key mediator of heat acclimation induced neuroprotection

Heat acclimation (HA), a well-established preconditioning model, confers neuroprotection in rodent models of traumatic brain injury (TBI). It increases neuroprotective factors, among them is hypoxia-inducible factor 1α (HIF-1α), which is important in the response to postinjury ischemia. However, lit...

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Hauptverfasser: Umschweif, Gali, Alexandrovich, Alexander G, Trembovler, Victoria, Horowitz, Michal, Shohami, Esther
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618386/
https://ncbi.nlm.nih.gov/pubmed/23281425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.193
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