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Enzyme inhibition of dopamine metabolism alters 6-[(18)F]FDOPA uptake in orthotopic pancreatic adenocarcinoma

BACKGROUND: An unknown location hampers removal of pancreatic tumours. We studied the effects of enzyme inhibitors on the uptake of 6-[(18)F]fluoro-l-3,4-dihydroxyphenylalanine ([(18)F]FDOPA) in the pancreas, aiming at improved imaging of pancreatic adenocarcinoma. METHODS: Mice bearing orthotopic B...

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Detalhes bibliográficos
Main Authors: Tuomela, Johanna, Forsback, Sarita, Haavisto, Laura, Vahlberg, Tero, Grönroos, Tove J, Solin, Olof, Haaparanta-Solin, Merja
Formato: Artigo
Idioma:Inglês
Publicado em: Springer 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618317/
https://ncbi.nlm.nih.gov/pubmed/23497589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-219X-3-18
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