Pharmacologic Inhibition of CXCL10 in Combination with Anti-malarial Therapy Eliminates Mortality Associated with Murine Model of Cerebral Malaria

Despite appropriate anti-malarial treatment, cerebral malaria (CM)-associated mortalities remain as high as 30%. Thus, adjunctive therapies are urgently needed to prevent or reduce such mortalities. Overproduction of CXCL10 in a subset of CM patients has been shown to be tightly associated with fata...

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Detalhes bibliográficos
Main Authors: Wilson, Nana O., Solomon, Wesley, Anderson, Leonard, Patrickson, John, Pitts, Sidney, Bond, Vincent, Liu, Mingli, Stiles, Jonathan K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618178/
https://ncbi.nlm.nih.gov/pubmed/23630573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060898
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