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Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter

In human cells, cytosolic citrate is a major precursor for the synthesis of fatty acids, triacylglycerols, cholesterol and low-density lipoprotein. Cytosolic citrate further regulates the cell’s energy balance by activating the fatty acid synthesis pathway while down-regulating both the glycolysis a...

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Bibliografiska uppgifter
Huvudupphovsmän: Mancusso, Romina, Gregorio, G. Glenn, Liu, Qun, Wang, Da-Neng
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617922/
https://ncbi.nlm.nih.gov/pubmed/23086149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11542
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