Tat peptide-decorated gelatin-siloxane nanoparticles for delivery of CGRP transgene in treatment of cerebral vasospasm

BACKGROUND: Gene transfer using a nanoparticle vector is a promising new approach for the safe delivery of therapeutic genes in human disease. The Tat peptide-decorated gelatin-siloxane (Tat-GS) nanoparticle has been demonstrated to be biocompatible as a vector, and to have enhanced gene transfectio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tian, Xin-Hua, Wang, Zhi-Gang, Meng, Han, Wang, Yu-Hua, Feng, Wei, Wei, Feng, Huang, Zhi-Chun, Lin, Xiao-Ning, Ren, Lei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2013
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617792/
https://ncbi.nlm.nih.gov/pubmed/23576867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S39951
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