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A Dicarboxylic Fatty Acid Derivative of Paclitaxel for Albumin Assisted Drug Delivery
Paclitaxel is a potent chemotherapy for many cancers but it suffers from very poor solubility. Consequently the TAXOL formulation uses copious amounts of the surfactant Cremophor EL to solubilize the drug for injection resulting in severe hypersensitivity and neutropenia. In contrast to Cremophor EL...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3617480/ https://ncbi.nlm.nih.gov/pubmed/22674061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23213 |
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