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A Classifier Based on Accurate Mass Measurements to Aid Large Scale, Unbiased Glycoproteomics

Determining which glycan moieties occupy specific N-glycosylation sites is a highly challenging analytical task. Arguably, the most common approach involves LC-MS and LC-MS/MS analysis of glycopeptides generated by proteases with high cleavage site specificity; however, the depth achieved by this ap...

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Detalhes bibliográficos
Main Authors: Froehlich, John W., Dodds, Eric D., Wilhelm, Mathias, Serang, Oliver, Steen, Judith A., Lee, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617326/
https://ncbi.nlm.nih.gov/pubmed/23438733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.025494
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