Hedgehog-Gli Activators Direct Osteo-chondrogenic Function of Bone Morphogenetic Protein toward Osteogenesis in the Perichondrium

Specification of progenitors into the osteoblast lineage is an essential event for skeletogenesis. During endochondral ossification, cells in the perichondrium give rise to osteoblast precursors. Hedgehog (Hh) and bone morphogenetic protein (BMP) are suggested to regulate the commitment of these cel...

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Autori principali: Hojo, Hironori, Ohba, Shinsuke, Taniguchi, Kiyomi, Shirai, Masataka, Yano, Fumiko, Saito, Taku, Ikeda, Toshiyuki, Nakajima, Keiji, Komiyama, Yuske, Nakagata, Naomi, Suzuki, Kentaro, Mishina, Yuji, Yamada, Masahisa, Konno, Tomohiro, Takato, Tsuyoshi, Kawaguchi, Hiroshi, Kambara, Hideki, Chung, Ung-il
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617292/
https://ncbi.nlm.nih.gov/pubmed/23423383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.409342
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