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Fine-tuning of Voltage Sensitivity of the K(v)1.2 Potassium Channel by Interhelix Loop Dynamics
Many proteins function by changing conformation in response to ligand binding or changes in other factors in their environment. Any change in the sequence of a protein, for example during evolution, which alters the relative free energies of the different functional conformations changes the conditi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3617271/ https://ncbi.nlm.nih.gov/pubmed/23413033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.437483 |
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