Hyperhomocysteinemia Promotes Insulin Resistance by Inducing Endoplasmic Reticulum Stress in Adipose Tissue

Type 2 diabetes is a chronic inflammatory metabolic disease, the key point being insulin resistance. Endoplasmic reticulum (ER) stress plays a critical role in the pathogenesis of type 2 diabetes. Previously, we found that hyperhomocysteinemia (HHcy) induced insulin resistance in adipose tissue. Her...

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Main Authors: Li, Yang, Zhang, Heng, Jiang, Changtao, Xu, Mingjiang, Pang, Yanli, Feng, Juan, Xiang, Xinxin, Kong, Wei, Xu, Guoheng, Li, Yin, Wang, Xian
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Molecular Bases of Disease
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617262/
https://ncbi.nlm.nih.gov/pubmed/23417716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.431627
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