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Heparanase Regulates Secretion, Composition, and Function of Tumor Cell-derived Exosomes

Emerging evidence indicates that exosomes play a key role in tumor-host cross-talk and that exosome secretion, composition, and functional capacity are altered as tumors progress to an aggressive phenotype. However, little is known regarding the mechanisms that regulate these changes. Heparanase is...

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Main Authors: Thompson, Camilla A., Purushothaman, Anurag, Ramani, Vishnu C., Vlodavsky, Israel, Sanderson, Ralph D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617250/
https://ncbi.nlm.nih.gov/pubmed/23430739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C112.444562
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