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Association of L-Ficolin Levels and FCN2 Genotypes with Chronic Chagas Disease

BACKGROUND: L-ficolin (encoded by FCN2) binds to acetylated sugar moieties of many pathogens, including Trypanosoma cruzi, promoting their phagocytosis and lysis by the complement system. METHODS: We investigated L-ficolin levels in 160 T. cruzi infected patients with chronic Chagas disease and 71 h...

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Hlavní autoři: Luz, Paola R., Boldt, Angelica B. W., Grisbach, Caroline, Kun, Jürgen F. J., Velavan, Thirumalaisamy P., Messias-Reason, Iara J. T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617223/
https://ncbi.nlm.nih.gov/pubmed/23593180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060237
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