ERCC1 and ERCC2 Haplotype Modulates Induced BPDE-DNA Adducts in Primary Cultured Lymphocytes

BACKGROUND: Benzo[a]pyrene(B[a]P), and its ultimate metabolite Benzo[a]pyrene 7,8-diol 9,10-epoxide (BPDE), are classic DNA damaging carcinogens. DNA damage caused by BPDE is normally repaired by Nucleotide Excision Repair (NER), of which ERCC1 and ERCC2/XPD exert an indispensable role. Genetic vari...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Lu, Xiaobo, Liu, Yanhua, Yu, Tao, Xiao, Sha, Bao, Xiaoyan, Pan, Liang, Zhu, Guolian, Cai, Yuan, Liu, Qiufang, Jin, Cuihong, Yang, Jinghua, Wu, Shengwen, An, Li, van der Straaten, Tahar
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617188/
https://ncbi.nlm.nih.gov/pubmed/23593158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060006
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker