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High Content Analysis of Primary Macrophages Hosting Proliferating Leishmania Amastigotes: Application to Anti-leishmanial Drug Discovery

BACKGROUND/OBJECTIVES: Human leishmaniases are parasitic diseases causing severe morbidity and mortality. No vaccine is available and numerous factors limit the use of current therapies. There is thus an urgent need for innovative initiatives to identify new chemotypes displaying selective activity...

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Detalhes bibliográficos
Main Authors: Aulner, Nathalie, Danckaert, Anne, Rouault-Hardoin, Eline, Desrivot, Julie, Helynck, Olivier, Commere, Pierre-Henri, Munier-Lehmann, Hélène, Späth, Gerald F., Shorte, Spencer L., Milon, Geneviève, Prina, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617141/
https://ncbi.nlm.nih.gov/pubmed/23593521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002154
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